LC

Liquid chromatography

We offer outstanding products of the highest quality for made-to-measure solutions and devices – without compromising product flexibility and dimensions for laboratories within the pharmaceutical and chemical sectors.

We provide support

We provide support. We create clarity. Get in contact, with us your concerns and queries are in good hands.

Jan Hirsch is your specialist in the field of HPLC systems.


Your contact person

Jan Hirsch

Systems

Standard design

  • LABOMATIC HD 5000 triple piston pumps
    • Flow rate: 5 – 2000 ml/min.
    • Pressure up to 600 bar
  • Binary to quaternary high- and low-pressure gradient elution
  • LABOPORT switch valve system
  • LABOPORT autosampler system
  • LABOCORD detectors
    • UV/VIS, DAD, RI, MS
  • LABOCOL Vario 4000 fraction collection series
  • LABOCHROM 5 software
  • Instrument layout systems

Customer-specific designs

  • Mobile system trolley
  • Integrated autosampler
  • Safety solvents cabinet with extraction device

ATEX compliant GMP system solutions 

  • Flow rates up to 5,000ml/min. and pressures up to 600 bar
  • Binary to quaternary gradient elution
  • Diverse autosampler solutions
  • Explosion-proof overpressure cabinet with integrated cooling system
  • Explosion-proof system switch valve
  • Continuous pressure, flow and temperature monitoring
  • Fibre optic cable photometer
  • Management and data processing system
  • System-integrated computer 

Devices

HD-5000 Pump

Power supply

  • The LABOMATIC HD-5000 can be operated with 120 V or 230 V (50 or 60 Hz) AC current.
  • The factory setting is done according to the customer's wish and can be changed as desired by the LABOMATIC Service Team.
  • The current setting is written on the back of the device.

System communication

  • RS 232
  • Ethernet
  • Analogs Voltage

Pumpheads specification

Specifications

HDK-280

HDK-360

HDK-570

HDK-810

HDK-1640

Mechanically achievable pressure

HDK-280: 900 bar

HDK-360: 675 bar

HDK-570: 430 bar

HDK-810: 300 bar

HDK-1640: 150 bar

Standard pressure

HDK-280: 450 bar

HDK-360: 350 bar

HDK-570: 250 bar

HDK-810: 200 bar

HDK-1640: 150 bar

ml/min

HDK-280: 280 ml/min

HDK-360: 360 ml/min

HDK-570: 570 ml/min

HDK-810: 810 ml/min

HDK-1640: 1640 ml/min

Features/advantages

  • By our Primary- / Secondary-Piston-System there are no mechanical forces from the drive to the primary piston. The primary piston is pressed against the secondary piston by a compression spring
  • A significantly lower wear of the primary piston seal through the use of aluminum oxide primary piston guide sleeves
  • Pressure or flow control
  • Piston backwash for a constant cleaning of the primary piston
  • Two different cam plates positive for suction or pressure side.
  • Much higher pressures can be generated with the HD-5000 pump. (Robert Bosch has been using the HD-5000 for many years in the production of vehicle injection nozzles with pressures up to 600 bar). 
  • We also have biocompatible Pump Systems

Devices

LABOMATIC HD-5000 triple-piston HPLC gradient pump

with integrated system controller for method programming and control of the complete HPLC system. The HD-5000 controller also allows binary, ternary or quaternary high pressure or low pressure gradient elution, with an almost pulsation-free flow.

Special features

  • Versions: Standard or GMP
  • Flow rates of 5 to 4,920 ml/min.
  • Three-piston system with primary and secondary pistons
  • Five different pump heads that can also be combined with each other
  • Pressures up to 600 bar (8,700 psi)
  • Active piston back rinse ensures easy use of buffer eluents
  • Up to quaternary high-pressure or low-pressure gradients
  • Active mixing system for low-pressure gradients
  • Control of 12 and more pump mechanics
  • Control of up to 20 valves, static or pulsed
  • Flow or constant pressure operation
  • Programmable flow gradient
  • Feeding with microlitre precision (e. g. DEA/TFA)

LABOPORT Ventile zur manuellen Probenaufgabe
LABOPORT Singel Probenaufgabe-System

Besondere Merkmale

  • Probenaufgabe-Ventil und Panel Diluter
  • Eine Probe einfach oder mehrfach aufgeben
  • Wird an den LABOMATIC Systempaneln montiert

LABOMAT AS-5000 AutoSampler

The instrument size is determined by the customer’s application, although the number of samples is limited due to the travel distance of 2,800 mm x 800 mm. The sample volume is virtually unlimited. The Z-axis moves up to 600 mm so correspondingly tall sample vessels can be used. The sample is either sucked into a sample loop with an appropriate diluting agent or a sample pump is used.

Special features    

  • Freely programmable XYZ system
  • Unlimited sample volume from microlitres to litres
  • Double cleaning of the needle to prevent sample transfer
  • Customised racks and/or fixing for round-bottomed flasks
  • Touchscreen for program and parameter display
  • or control via the LABOCHROM 5 software
  • A combination with a fraction collector is easily possible

See also LABOMAT LH-5000 Liquid Handling Systems

LABOCHROM AMC axially compressible chromatography columns for MPLC and HPLC

The axially compressible LABOCHROM AMC column for MPLC and HPLC chromatography is the only column of its kind. It is constantly under a pressure specified by the user, under which it is maintained independently of the operating pressure of the system. The axial compression makes the bed more stable and durable. Pressures of up to 65 bar allow a smaller gel particle size to be selected for the same application. The field of application ranges from preparative MPLC to a variety of applications in preparative HPLC.

Special features    

  • Axially compressible
  • Automatic packing and emptying
  • The best packing results obtained using axial pressure
  • Variable bed lengths due to the column seal which is adjustable by 500 mm
  • 20 different dimensions with pressures up to 65 bar (see range)
  • Spring-supported column seals
  • Prevention of wall effects by using precision tubes made of stainless steel or borosilicate glass
  • The cartridge system helps reduce operating costs
  • Compressing units for different column diameters can be used
  • Completely independent of external power sources      

LABOCHROM ACSC axially compressible HPLC chromatography steel columns

The axially compressible LABOCHROM ACSC-HPLC column is the only column of its kind. Like the AMC column, it is under a constant pressure specified by the user, under which it is maintained independently of the operating pressure of the system. The axial compression makes the bed more stable and durable.

Special features     

  • Axially compressible
  • Automatic packing and emptying
  • Best packing results obtained using axial pressure
  • Variable bed lengths due to the column seal which is adjustable by 500 mm
  • 20 different dimensions with pressures up to 150 bar (see range)
  • Spring-supported column seals
  • Prevention of wall effects due to the use of precision stainless steel tubes
  • The cartridge system helps reduce operating costs
  • Compressing units for different column diameters can be used
  • Completely independent of external power sources    

LABOCHROM HDSC HPLC steel chromatography columns

Area of application

HPLC (High Performance Liquid Chromatography) for research, development and production.

Special features    

  • Inner diameter from 10 to 50 mm
  • Lengths up to 250 mm
  • Empty columns or packed columns 

LABOCHROM MPGC glass columns for medium pressure (MPLC) and flash chromatography

The LABOCHROM MPGC columns are the only glass columns with a column seal that can be adjusted under pressure. The field of application includes MPLC (medium pressure chromatography) and flash chromatography.

Special features    

  • No dead volume due to the pressurised column seal with an adjustable height of 40 mm
  • Withstands pressure up to 20 bar
  • 38 different column dimensions (see range)
  • Precolumns for all inner diameters
  • Columns are made of inert materials (PTFE, glass)
  • Good chromatographic results due to optimal inner column surface made of glass
  • Visual observation of the packing status
  • Reproducible and even sample distribution due to the conical shape of the inlet
  • Couplings available for connecting columns with various different inner diameters

LABOCORD-5000 diode array (DAD) and UV/VIS spectrophotometer

Combines the attractive and functional LABOMATIC design with high-performance photometer technology. Its specifications, robustness and high flexibility are impressive.

Special features    

  • Versions: Standard or GM
  • Large number of measuring cells available
  • Preparative measuring cells with layer thicknesses of 0.05 mm minimum
  • Flow rate up to 10 litre/min.
  • Measuring cells with optical fibres (ATEX)

LABOMATIC Vario-4000 fraction collection series

Small-sized instruments for a large number of fractions

The small size combined with optimum space utilisation make the LABOCOL Vario-4000 units ideal for use where space is limited.

The series consists of the following units.

  • Vario-4000 with a fractioning area for three racks of one type.
  • Vario-4000 Plus with a fractioning area for five racks of one type.
  • Vario-4000 X-Plus, a unit tailored to individual customer needs. Any fractionating vialscan be placed on a base area of maximum 49 x 57 cm (width x depth). We manufacture individual racks for you.

Fractions up to several litres are possible.

Special features

  • Versions: Standard or GMP
  • Removable XY system, also for use with drain racks
  • Freely programmable XY system
  • Height-adjustable fraction collection arm
  • Touchscreen panel as programming console
  • Fractionation time or pump delivery volume programming
  • Variety of different fractionation racks
  • No problems with aggressive solvents due to the use of stainless steel for housing and test tube racks
  • Small size combined with optimal space utilisation
  • Flow interruption and delay/waste valve integrated into the unit
  • Up to one litre fractionation volume.
  • Draining racks for collecting up to 100 fractions of any volume
  • Choice of fractionation vials with different capacities from a few millilitres up to one litre
  • Multiple chromatography, simultaneous dosing of up to 20 column fractions simultaneously